Immunodeficiency with hyper IgM type 1
Other Names for this Disease
- Hyper IgM immunodeficiency, x-linked
- Hyper IgM syndrome
- Hyper IgM syndrome 1
How might hyper IgM syndrome be treated?
Hyper IgM syndromes are characterized by normal or elevated serum immunoglobulin M levels with absence of immunoglobulin G, A, and E. Immunoglobulins are proteins found in the blood. Hyper IgM results in a susceptibility to bacterial infections and sometimes opportunistic infections. There are five different types of hyper IgM syndromes (types 1-5). The types are distinguished by the location of the gene mutation involved.
Most children with hyper-IgM syndrome respond well to treatment, become symptom-free and resume normal growth.
- Primary Immunodeficiency. National Institute of Child Health and Human Development (NICHD) . April 7, 2008; http://www.nichd.nih.gov/publications/pubs/primary_immuno.cfm#WhatisPrimaryImmunodeficiency. Accessed 10/12/2010.
- Hyper IgM Immunodeficiency Syndrome. MeSH. http://www.nlm.nih.gov/cgi/mesh/2008/MB_cgi?mode=&index=24001&field=all&HM=&II=&PA=&form=&input=. Accessed 4/16/2008.
- Primary Immunodeficiency Diseases: Some Examples. National Institute of Child Health and Human Development (NICHD). April 7, 2008; http://www.nichd.nih.gov/publications/pubs/pages/primary_immuno.aspx. Accessed 4/16/2008.
- Hyper IgM Immunodeficiency. Primary Immunodeficiency Resource Center. 2008; http://www.info4pi.org/aboutPI/index.cfm?section=aboutPI&content=syndromes&area=13&CFID=4740438&CFTOKEN=e428d93702237370-4B49B0F6-0023-0F1A-C289B29F1FE43C9A. Accessed 4/16/2008.