Other Names for this Disease
- Broad gyri of cerebrum
- Large gyri of cerebrum
Your QuestionI have been diagnosed with pachygyria (macrogyria). I don't have mental retardation, in fact I have a high IQ. I have severe migraines and recently started having seizures. Could pachygyria be causing my problems? Are there any other problems that could be caused by pachygyria? Is there a treatment for it? Also, what is pseudobulbar palsy?
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Questions on this page
Pseudobulbar palsy is caused by lesions of the corticobulbar tracts (upper motor neurons). These tracts contain nerves which control muscles of the head and face (including the pharynx, palate, lips, tongue, and larynx). The lesions may develop in association with strokes, blood cancers (leukemia), or trauma. Pseudobulbar palsy can also occur in association with CADASIL, progressive supranuclear palsy, central pontine myelinolysis, congenital bilateral perisylvian syndrome, pachygyria and acquired epileptiform opercular syndrome (seizure induced symptoms).
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- Kuzniecky R, Andermann F, Tampieri D, Melanson D, Olivier A, Leppik I. Bilateral central macrogyria: epilepsy, pseudobulbar palsy, and mental retardation--a recognizable neuronal migration disorder. Ann Neurol. 1989 Jun; 25(6):547-554. http://www.ncbi.nlm.nih.gov/pubmed/2500888. Accessed 11/21/2013.
- NINDS Neuronal Migration Disorders Information Page. National Institute of Neurological Disorders and Stroke (NINDS) Web site. 2007; http://www.ninds.nih.gov/health_and_medical/disorders/neuronal_migration.htm. Accessed 8/18/2009.
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