Print friendly version
Pachygyria
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
Overview
Pachygyria is a rare developmental disorder which results from abnormal migration of neurons in the developing brain and nervous system.[1] In pachygyria, the gyri are relatively few and are unusually broad and flat. The condition does not affect the entire brain, and is also known as ‘incomplete lissencephaly.’[2] Symptoms are variable, but may include seizures, developmental delay, growth failure, small head size, feeding issues and poor muscle control.[1] Most cases are isolated, although autosomal dominant and recessive forms have been described.[1][3] Treatment is symptomatic and supportive.[1][2]
References
- NINDS Neuronal Migration Disorders Information Page. National Institute of Neurological Disorders and Stroke (NINDS) Web site. http://www.ninds.nih.gov/health_and_medical/disorders/neuronal_migration.htm. Accessed August 18, 2009.
- Grainger & Allison's Diagnostic Radiology: A Textbook of Medical Imaging, 4th ed.. 2001.
- Straussberg R, Gross S, Amir J, Gadoth N. Clin Genet. 1996. http://www.ncbi.nlm.nih.gov/pubmed/9147882. Accessed August 18, 2009.
Your Questions Answered
by the Genetic and Rare Diseases Information Center1 question(s) from the public on Pachygyria have been answered. See questions and answers. You can also submit a new question.
On this page
General Information
- The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Pachygyria. Click on the link to view a sample search on this topic.
- The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Pachygyria. Click on the link to go to OMIM and review these resources.