Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Papular mucinosis

Other Names for this Disease
  • Lichen myxedematosus
  • Lichen myxoedematosus
  • Localized lichen myxedematosus
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Papular mucinosis is a rare skin disorder characterized by deposits of mucin in the skin. The terms "papular mucinosis" and "lichen myxoedematosus" are generally used interchangeably to describe the occurrence of this condition as a localized and less severe form, while the term scleromyxoedema refers to a generalized, more severe form.[1][2] Signs and symptoms of the condition include the presence of small, firm, waxy papules on the skin that are confined to a few sites on the body.[1] Affected individuals are typically otherwise healthy.[2] The cause of the condition is unknown, but it is commonly associated with monoclonal gammopathy. It has also been reported in association with bone marrow cancers as well HIV infection, hepatitis C, exposure to toxic oil and contaminated L-tryptophan.[1] Localized papular mucinosis typically does not require therapy, but topical corticosteroids and oral isotretinoin may help to reduce hardening of the skin.[1]
Last updated: 3/19/2012


  1. Lichen myxoedematosus. DermNet NZ. June 29, 2011; Accessed 3/19/2012.
  2. Elizabeth A Liotta. Lichen Myxedematosus. eMedicine. January 17, 2012; Accessed 3/19/2012.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

1 question(s) from the public on Papular mucinosis have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Papular mucinosis. Click on the link to view a sample search on this topic.