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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Pars planitis


Other Names for this Disease
  • Familial pars planitis (subtype)
  • Intermediate uveitis
  • Peripheral retinal inflammation
  • Vitritis
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Overview



What is pars planitis?

How might pars planitis be treated?


What is pars planitis?

Pars planitis is a disease of the eye in which there is inflammation of the pars plana, a small area of tissue next to the iris that is responsible for making aqueous humor (the fluid in the eye that nourishes the lens and cornea).  Pars planitis is often referred to as intermediate uveitis because the pars plana is a part of the uvea.[1][2]  This condition most often affects young men and is generally not associated with any other disease or symptoms (idiopathic).[1] However, there have been a few case reports of an association with Crohn's disease, and some experts suggest a possible association with multiple sclerosis, sarcoidosis, cat scratch or Lyme disease.[1][2]
Last updated: 4/8/2012

How might pars planitis be treated?

The first approach to treating pars planitis is to inject steroids near the eye to control inflammation.  If several injections are given without success, non-steroidal anti-inflammatory drugs (NSAIDs, including aspirin) or steroid medications (such as prednisone) may be taken by mouth.  If these are also unsuccessful, other medications may be given to reduce the body's immune responses (medications called immunosuppressants, such as methotrexate). 

If medications are not effective, surgery may be considered.  Cryosurgery has been performed in affected individuals to remove eye tissue that has inflammation.  Although this surgery has been shown to be effective in restoring clarity of vision, there are concerns that it may cause damage to other parts of the eye.  Another surgery, known as vitrectomy, can be done to remove cloudy fluid (vitreous humor) from the eye.[3]
Last updated: 4/8/2012

References
  1. Vorvick L, Lusby FW. Uveitis. MedlinePlus. 2010; http://www.nlm.nih.gov/medlineplus/ency/article/001005.htm. Accessed 6/8/2011.
  2. Foster S. Treatment Algorithm for Pars Planitis. Ocular Immunology and Uveitis Foundation. http://www.uveitis.org/medical/treatment/algo4.html. Accessed 6/8/2011.
  3. Prieto JF, Dios E, Gutierrez JM, Mayo A, Calonge M, Herreras JM. Pars planitis: epidemiology, treatment, and association with multiple sclerosis. Ocular immunology and inflammation. 2001; 9:93-102. http://www.ncbi.nlm.nih.gov/pubmed/11449325. Accessed 4/3/2012.