Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Peeling skin syndrome

Other Names for this Disease
  • Deciduous skin
  • Familial continuous skin peeling
  • Keratolysis exfoliativa congenita
  • Peeling skin syndrome, acral type (subtype)
  • Peeling skin syndrome, inflammatory type B (subtype)
More Names
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Newline Maker

How might peeling skin syndrome be treated?

There is currently no cure for peeling skin syndrome and unfortunately, no effective treatment has been reported. Topical emollients (skin softening ointments) may help; plain petroleum jelly has been used by some individuals.[1][2] Keratolytic agents might speed up shedding and improve appearance. Treatments such as methotrexate, UVB phototherapy, isotretinoin, and oral corticosteroid therapy have been found to be ineffective in past studies.[1]
Last updated: 6/13/2011

  1. Kshitij Garg, Devesh Singh, Devesh Mishra. Peeling skin syndrome: Current status. Dermatology Online Journal. March 2010; 16(3):10. Accessed 6/13/2011.
  2. Peeling Skin Syndrome. NORD. October 18, 2010; Accessed 6/13/2011.

Clinical Trials & Research for this Disease

  • Orphanet lists clinical trials, research studies, and patient registries enrolling people with this condition. Click on Orphanet to view the list.