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Genetic and Rare Diseases Information Center (GARD)

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Perniosis


Other Names for this Disease
  • Chilblains
  • Cold-induced painful or pruritic erythematous or violaceous acral papular or nodular lesions
  • Idiopathic perniosis
  • Pernio
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Overview

Perniosis are itchy and/or tender red or purple bumps that occur as a reaction to cold. In severe cases blistering, pustules, scabs and ulceration can occur. Occasionally the lesions may be ring-shaped. They may become thickened and persist for months. Perniosis is a form of vasculitis. Signs and symptoms occur hours after cold exposure. Risk factors for perniosis include, having poor blood circulation (such as due to diabetes or smoking), a family history of perniosis, poor nutrition, and low body weight. Perniosis may occur alone or in association with an autoimmune condition (e.g., lupus, scleroderma), bone marrow disorder, or cancer. Treatment aims to relieve itching and swelling, prevent infection, and lifestyle/adaptive changes to prevent future symptoms.[48124]
Last updated: 1/20/2015

References

  1. Chilblains. DermNet NZ. http://dermnetnz.org/reactions/chilblains.html. Accessed 1/20/2015.
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1 question(s) from the public on Perniosis have been answered. See questions and answers . You can also submit a new question.

Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Perniosis. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Chilblains
  • Cold-induced painful or pruritic erythematous or violaceous acral papular or nodular lesions
  • Idiopathic perniosis
  • Pernio
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.