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Peyronie disease

Other Names for this Disease
  • Penile curvature
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Peyronie disease is a rare connective tissue disorder characterized by a plaque, or hard lump, that forms within the penis.[1] Affected individuals may experience painful, curved erections which can make make normal sexual intercourse impossible. Symptoms may appear suddenly or develop gradually.[2][3] While the painful erections for most men resolve over time, the scar tissue and curvature may remain.[3] Some cases appear to resolve spontaneously.[2][3] The exact cause of Peyronie's disease is not known.[1][2]
Last updated: 11/23/2011


  1. Peyronie's Disease. National Kidney & Urologic Diseases. September 2010; Accessed 11/23/2011.
  2. Hellstrom WJ. Peyronie's Disease. National Organization for Rare Disorders (NORD). 2009; Accessed 11/23/2011.
  3. Peyronie's disease. August 2011; Accessed 11/23/2011.
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Basic Information

  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC), part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), conducts and supports research on a broad spectrum of diseases affecting public health. Click on the link to view information on this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Peyronie disease. Click on the link to view a sample search on this topic.