Other Names for this Disease
- Liddle's syndrome
- Pseudohyperaldosteronism type 1
Tests & Diagnosis
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A diagnosis of Liddle syndrome may first be suspected by the detection of early-onset hypertension (high blood pressure), especially in the presence of family history. The diagnosis may then be confirmed by special blood and urine tests which show hypokalemia (low blood potassium levels), decreased or normal plasma levels of renin and aldosterone, metabolic alkalosis with high sodium plasma levels, and low rates of urinary excretion of sodium and aldosterone with high rates of urinary potassium excretion. The diagnosis can be further confirmed by genetic testing.
Last updated: 9/21/2012
- Rosa Vargas-Poussou. Liddle syndrome. Orphanet. August 2011; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=526. Accessed 9/21/2012.