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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Pheochromocytoma


Other Names for this Disease

  • Chromaffin cell tumor
  • Chromaffin paraganglioma
  • Chromaffin tumor
  • Chromaffinoma
  • Medullary paraganglioma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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How might pheochromocytoma be treated?

The recommended treatment of a pheochromocytoma is removal by surgery, even in cases where there are pheochromocytomas in both adrenal glands.[1]  Prior to surgery, it is important to take medications to control and stabilize blood pressure.  Following surgery, affected individuals should visit their physicians regularly to monitor blood pressure and blood levels of metanephrine.[2][3]  Long-term treatment with medication should only be considered if, for some reason, the pheochromocytoma cannot be removed by surgery.[2]
Last updated: 8/24/2014

References
  1. Gumbs AA, Gagner M. Laparoscopic adrenalectomy. Best Practice & Research Clinical Endocrinology & Metabolism. 2006; 20(3):483-499. http://www.ncbi.nlm.nih.gov/pubmed/16980207. Accessed 8/24/2014.
  2. Sweeney AT. Pheochromocytoma. eMedicine. June 2014; http://emedicine.medscape.com/article/124059-overview. Accessed 8/24/2014.
  3. National Comprehensive Cancer Network. Neuroendocrine Tumors. NCCN Clinical Practice Guidelines in Oncology. 2014; http://www.nccn.org/professionals/physician_gls/pdf/neuroendocrine.pdf. Accessed 11/22/2014.


Management Guidelines

  • GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions. Click on the link to view the article on this topic.

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Pheochromocytoma. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.

Medical Products

The medication(s) listed in the table(s) below have been approved by the Food and Drug Administration (FDA) for treatment of this condition. The FDA Office of Orphan Products Development designates "orphan products" for those that treat rare diseases affecting fewer than 200,000 Americans. The table(s) below may not be an exhaustive list of drugs or products used to treat this condition. There may be other products available that are not considered orphan products. To search for all FDA approved drugs, visit Drugs@FDA. You can find orphan products used to treat other conditions by searching the Orphan Drug Product Designation database.


Generic Name Iobenguane I 123
Trade Name
(Manufacturer Name)
Adreview™
(GE Healthcare, Inc)
Indication
The FDA has approved this product to be used in this manner.
To be used in the detection of primary or metastatic pheochromocytomas or neuroblastomas as an adjunct to other diagnostic tests
More Information about this product Drug Information Portal

Generic Name Iobenguane sulfate I 131
Trade Name
(Manufacturer Name)
I-131 MIBG®
(Pharmalucence)
Indication
The FDA has approved this product to be used in this manner.
Adjunctive diagnostic agent in the localization of primary or metastatic pheochromocytomas.
More Information about this product Drug Information Portal

Other Names for this Disease
  • Chromaffin cell tumor
  • Chromaffin paraganglioma
  • Chromaffin tumor
  • Chromaffinoma
  • Medullary paraganglioma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.