Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Pityriasis rubra pilaris


Other Names for this Disease

  • Familial pityriasis rubra pilaris
  • Pityriasis rubra pilaris--familial type
  • PRP
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Your Question

Is there any research currently being conducted on pityriasis rubra pilaris? How can I learn more about research findings?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

Is there any research currently being conducted on pityriasis rubra pilaris? How can I learn more about research findings?

The U.S. National Institutes of Health, through the National Library of Medicine, developed ClinicalTrials.gov to provide patients, family members, and members of the public with current information on clinical research studies. Clinicaltrials.gov lists that there was a study titled A Pilot Study of Alefacept for the Treatment of Pityriasis Rubra Pilaris, however the study was termintated due to a failure to enroll patients. Click on the link below to learn more about this trial.
http://clinicaltrial.gov/ct2/show/NCT00815633

There is a study titled  Evaluation and Treatment of Patients with Dermatologic Diseases that is enrolling people with skin conditions in general, and may be of interest to you. Click on the study title to learn more.

You can also contact the Patient Recruitment and Public Liaison (PRPL) Office at the National Institutes of Health (NIH). We recommend calling the toll-free number listed below to speak with a specialist, who can help you determine if you are eligible for any clinical trials.

Patient Recruitment and Public Liaison Office
NIH Clinical Center
Bethesda, Maryland 20892-2655
Toll-free: 800-411-1222
Fax: 301-480-9793
Email: prpl@mail.cc.nih.gov
Web site:  http://clinicalcenter.nih.gov/

If you are interested in enrolling in a clinical trial, you can find helpful general information on clinical trials at the following ClinicalTrials.gov Web page.
http://clinicaltrials.gov/ct2/info/understand

Resources on many charitable or special-fare flights to research and treatment sites and low-cost hospitality accommodations for outpatients and family members, as well as ambulance services, are listed on the Web site of the Office of Rare Diseases Research (ORDR), part of the National Institutes of Health.
http://rarediseases.info.nih.gov/Resources.aspx?PageID=8

The Research Portfolio Online Reporting Tool (RePORT) provides access to reports, data, and analyses of research activities at the National Institutes of Health (NIH). There is a study titled Dermatology Consultation Clinic and Clinical Research that may be of interest to you. You may want to contact the investigator, Maria Turner (maria.turner@nih.gov) to learn more.

Searching the medical literature is a way to find recent articles summarizing research study or clinical trial results. You can use PubMed.gov at the following link to search for articles. Using 'pityriasis rubra pilaris' as your search term should locate articles.
http://PubMed.gov/

To give you and idea of the type of articles you can find by searching PubMed.gov we have listed a few articles that we identified through our search that may be of interest to you.

Klein A, Landthaler M, Karrer S. Pityriasis rubra pilaris: a review of diagnosis and treatment. Am J Clin Dermatol. 2010;11(3):157-70.

Sehgal VN, Srivastava G, Dogra S. Adult onset pityriasis rubra pilaris. Indian J Dermatol Venereol Leprol. 2008 Jul-Aug;74(4):311-21.

Liao WC, Mutasim DF. Infliximab for the treatment of adult-onset pityriasis rubra pilaris. Arch Dermatol. 2005 Apr;141(4):423-5.

Müller H, Gattringer C, Zelger B, Höpfl R, Eisendle K. Infliximab monotherapy as first-line treatment for adult-onset pityriasis rubra pilaris: case report and review of the literature on biologic therapy. J Am Acad Dermatol. 2008 Nov;59(5 Suppl):S65-70.


Some articles in PubMed.gov are available as a complete document, while information on other studies is available as a summary abstract.  The National Library of Medicine (NLM) can help you locate libraries in your area that can provide direct access to these journals. You can contact the NLM toll-free at 888-346-3656.

Last updated: 9/20/2010
Other Names for this Disease
  • Familial pityriasis rubra pilaris
  • Pityriasis rubra pilaris--familial type
  • PRP
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.