Other Names for this Disease
- Poland anomaly
- Poland sequence
- Poland syndactyly
- Poland's syndrome
- Unilateral defect of pectoralis muscle and syndactyly of the hand
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The cause of Poland syndrome is unknown. Most evidence supports the idea that something abnormal happens during the sixth week of fetal development. This event most likely involves the vascular (blood and lymph) system. Speculations include:
- An interruption of the embryonic blood supply of the arteries that lie under the collarbone (subclavian arteries). This could be caused by the forward growth of the ribs reducing the flow of blood.
- A malformation of the subclavian arteries causes a reduced amount of blood delivered to the developing tissues on one side of the body.
Last updated: 6/25/2011
- Learning About Poland Anomaly. National Human Genome Research Institute. June 28, 2010; http://www.genome.gov/14514230. Accessed 9/30/2010.