Print friendly version
Progressive multifocal leukoencephalopathy
Other Names for this Disease
- Leukoencephalopathy, progressive multifocal
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
myelin that covers and protects nerves in the white matter of the brain. It is caused by the JC virus (JCV). By age 10, most people have been infected with this virus, but it rarely causes symptoms unless the immune system becomes severely weakened. The disease occurs, rarely, in organ transplant patients; people undergoing chronic corticosteroid or immunosuppressive therapy; and individuals with cancer, such as Hodgkin’s disease, lymphoma, and sarcoidosis. PML is most common among individuals with acquired immune deficiency syndrome (AIDS).Progressive multifocal leukoencephalopathy (PML) is a neurological disorder that damages the
Last updated: 4/1/2011
- Dugdale DC, Jasmin L. Progressive multifocal leukoencephalopathy. MedlinePlus. 2010; http://www.nlm.nih.gov/medlineplus/ency/article/000674.htm. Accessed 3/3/2011.
- Koralnik IJ. Progressive Multifocal Leukoencephalopathy. National Organization for Rare Disorders (NORD). 2010; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Progressive%20Multifocal%20Leukoencephalopathy. Accessed 3/3/2011.
- NINDS Progressive Multifocal Leukoencephalopathy Information Page. National Institute of Neurological Disorders and Stroke (NINDS). 2010; http://www.ninds.nih.gov/disorders/pml/pml.htm. Accessed 3/3/2011.
Your Questions Answeredby the Genetic and Rare Diseases Information Center
Please contact us with your questions about Progressive multifocal leukoencephalopathy. We will answer your question and update these pages with new resources and information.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
In Depth Information
- Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Progressive multifocal leukoencephalopathy. Click on the link to view a sample search on this topic.
- The Social Security Administration has included this condition in their Compassionate Allowances Initiative. This initiative speeds up the processing of disability claims for applicants with certain medical conditions that cause severe disability. More information about Compassionate Allowances and applying for Social Security disability is available online.