Progressive supranuclear palsy
Other Names for this Disease
- Familial progressive supranuclear palsy (type)
- Steele-Richardson-Olszewski Syndrome
- Supranuclear palsy, progressive
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Another group of drugs that has been of some modest success in progressive supranuclear palsy are antidepressant medications. The most commonly used of these drugs are fluoxetine (Prozac), amitriptyline (Elavil), and imipramine (Tofranil). The benefit of these drugs seems not to be related to their ability to relieve depression.
Non-drug treatment for progressive supranuclear palsy can take many forms. Patients frequently use weighted walking aids because of their tendency to fall backward. Bifocals or special glasses called prisms are sometimes prescribed for patients to remedy the difficulty of looking down. Although formal physical therapy has not proven helpful in progressive supranuclear palsy, certain exercises can be done to keep the joints limber.
A surgical procedure that may be necessary when there are swallowing disturbances is a gastrostomy. A gastrostomy (or a jejunostomy) is a minimally invasive procedure which is performed when the patient has difficulty swallowing or when severe choking is a definite risk. This surgery involves the placement of a tube through the skin of the abdomen into the stomach (intestine) for feeding purposes.Additional information about treatment of progressive supranuclear palsy can be obtained through the following web pages developed by WE MOVE and Cure PSP:
- Progressive Supranuclear Palsy Fact Sheet. National Institute for Neurological Disorders and Stroke (NINDS). August 16, 2011; http://www.ninds.nih.gov/disorders/psp/detail_psp.htm. Accessed 8/18/2011.
- GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions. Click on the link to view the article on this topic.
Clinical Trials & Research for this Disease
- ClinicalTrials.gov lists trials that are studying or have studied Progressive supranuclear palsy. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.