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Genetic and Rare Diseases Information Center (GARD)

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Pseudocholinesterase deficiency

Other Names for this Disease
  • Apnea, Postanesthetic
  • Butyrylcholinesterase deficiency
  • Cholinesterase 2 Deficiency
  • Pseudocholinesterase E1
  • Succinylcholine Sensitivity
More Names
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What treatment is available for pseudocholinesterase deficiency?

Individuals with pseudocholinesterase deficiency should avoid exposure to exogenous (outside of the body) sources of choline esters. The mainstay of treatment for patients in the midst of prolonged paralysis is mechanical ventilatory support until respiratory muscle paralysis spontaneously resolves. Recovery eventually occurs as a result of passive diffusion of succinylcholine away from the neuromuscular junction.[1]
Last updated: 3/3/2010

  1. Daniel R Alexander. Pseudocholinesterase Deficiency. eMedicine. July 17, 2006; Accessed 9/4/2008.