Other Names for this Disease
- Rosaï-Dorfman disease
- Sinus histiocytosis with massive lymphadenopathy
The symptoms and physical findings associated with Rosai-Dorfman disease vary depending upon the specific areas of the body that are affected. Systemic symptoms, such as fever, weight loss, malaise, joint pain, and night sweats, may be present. Cervical lymph nodes are most characteristically involved, but other areas, including extranodal regions, can be affected. These areas include the skin, central nervous system, kidney, and digestive tract.
Last updated: 7/22/2013
- Rosai J. Rosai-Dorfman Disease. National Organization for Rare Disorders (NORD). 2011; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1122/viewAbstract. Accessed 7/22/2013.
- Tebbi CK, Arceci RJ, Loew TW. Histiocytosis. Medscape Reference. April 2012; http://emedicine.medscape.com/article/958026-overview. Accessed 7/22/2013.