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Autoimmune polyglandular syndrome type 2
Other Names for this Disease
- Autoimmune polyendocrine syndrome type 2
- Diabetes mellitus, Addison's disease, myxedema
- Multiple endocrine deficiency syndrome, type 2
- PGA 2
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Autoimmune polyglandular syndrome type 2 is an autoimmune disorder that affects many hormone-producing (endocrine) glands. This condition is characterized by the presence of Addison's disease along with autoimmune thyroid disease and/or type 1 diabetes. Affected individuals may also have problems with other endocrine glands. Autoimmune polyglandular syndrome type 2 is diagnosed in adulthood, typically around age 30. This condition occurs more often in women than men, and treatment primarily involves hormone replacement therapy. The cause of autoimmune polyglandular syndrome type 2 is unknown, although it may involve a combination of genetic and environmental factors.
- Sivarajah S, Fan CY, Akinsoto OPA. Polyglandular Autoimmune Syndrome, Type II. eMedicine Journal. http://emedicine.medscape.com/article/124287-overview. Accessed March 24, 2010.
- Polyglandular Deficiency Syndromes. Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec12/ch154/ch154a.html. Accessed March 24, 2010.
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- Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
- The Merck Manuals Online Medical Library provides information on this condition. Click on the link to view the information.
- The National Endocrine and Metabolic Diseases Information Service, a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), provides information on this topic. Click on the link to view the information on this topic.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. Click on the link to read information on this topic.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Autoimmune polyglandular syndrome type 2. Click on the link to view a sample search on this topic.
- The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Autoimmune polyglandular syndrome type 2. Click on the link to go to OMIM and review these resources.