Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Sezary syndrome


Other Names for this Disease
  • Sézary syndrome
  • Sezary's lymphoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Inheritance


Newline Maker

Is Sezary syndrome inherited?

To our knowledge, there have not been any reports of familial cases of Sezary syndrome (e.g. the condition occurring in more than one member of a family), and the exact cause of the condition is currently unknown.[1]

A closely related condtion, mycosis fungoides (MF), has been reported to occur in more than one family member in several families.[1] Sezary syndrome has been considered a "leukemic variant" of MF in the past.[2] However, although there are conflicting reports in the literature, they are now more commonly thought to be separate conditions.
Last updated: 2/27/2013

References
  1. Hodak E. et al. Familial mycosis fungoides: report of 6 kindreds and a study of the HLA system. J Am Acad Dermatol. March 2005; 52(3 Pt 1):393-402.
  2. Cutaneous T-Cell Lymphomas. NORD. January 3, 2007; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1124/viewAbstract. Accessed 4/30/2012.