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Stevens-Johnson syndrome

Other Names for this Disease
  • Erythema multiforme major
  • SJS
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Stevens-Johnson Syndrome (SJS), also called erythema multiforme major, is a limited form of toxic epidermal necrolysis. This disorder affects the skin, mucous membranes and eyes.[1][2] Stevens-Johnson syndrome occurs twice as often in men as women, and most cases appear in children and young adults under 30, although it can develop in people at any age.[1] It is an emergency medical condition that usually requires hospitalization. Treatment focuses on eliminating the underlying cause, controlling symptoms and minimizing complications.[3]
Last updated: 11/22/2010


  1. Facts About The Cornea and Corneal Disease. National Eye Institute (NEI). 2010; Accessed 3/15/2010.
  2. Roujeau JC. Stevens-Johnson syndrome. Orphanet. 2009; Accessed 3/15/2010.
  3. Stevens-Johnson syndrome. 2009; Accessed 3/15/2010.
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Basic Information

  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The Merck Manuals Online Medical Library provides information on this condition. Click on the link to view the information.
  • The National Eye Institute (NEI) was established by Congress in 1968 to protect and prolong the vision of the American people. Click on the link to view information on this topic. 
  • provides information about Stevens-Johnson syndrome.

In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Stevens-Johnson syndrome. Click on the link to view a sample search on this topic.
  • Medscape Reference has 4 articles on this topic from the perspective of Emergency Medicine, Infectious Diseases, Ophthalmology and Dermatology. You may need to register to view the information online, but registration is free.