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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Superior mesenteric artery syndrome


Other Names for this Disease

  • Arteriomesenteric duodenal compression syndrome
  • Cast syndrome
  • Vascular compression of the duodenum
  • Wilkie syndrome
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Cause

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What causes superior mesenteric artery syndrome?

A variety of factors can contribute to the development of superior mesenteric artery syndrome (SMAS), including:
  • prolonged bed rest
  • rapid, severe weight loss
  • rapid growth
  • previous abdominal surgery
  • lordosis
  • use of body casts
  • loss of tone in abdominal muscles

SMAS has also been reported to occur in some people with pancreatitis, peptic ulcers, and other inflammatory conditions in the abdomen.[1] Rarely, the condition may be caused by an anatomical abnormality (such as unusual position or location of the artery). Familial SMAS, recurrent SMAS, and idiopathic neonatal SMAS have also been reported.[2]

Last updated: 3/26/2014

References
  1. Juan-R. Malagelada, Carolina Malagelada . Chapter 8 - Nausea and Vomiting. In: Mark Feldman, Lawrence S. Friedman, Lawrence J. Brandt. Sleisenger & Fordtran's Gastrointestinal and Liver Disease, 8th edition. Philadelphia, PA : Saunders Elsevier; 2006;
  2. Frederick Merrill Karrer. Superior Mesenteric Artery Syndrome. Medscape Reference. September 4, 2012; http://emedicine.medscape.com/article/932220-overview. Accessed 3/26/2014.


Other Names for this Disease
  • Arteriomesenteric duodenal compression syndrome
  • Cast syndrome
  • Vascular compression of the duodenum
  • Wilkie syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.