Tests & Diagnosis
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A doctor may use the following procedures and tests to diagnose synovial sarcoma:
- Biopsy: Tissue is removed for examination under a microscope.
- Immunohistochemical analysis: Tumor tissue is tested for certain antigen and antibody interactions common to synovial sarcoma.
- Ultrastructural findings: The tissue is examined using an ultramicroscope and electron microscope.
- Genetic testing: Tissue is tested for a specific chromosome abnormality common to synovial sarcoma. The characteristic chromosome translocation t(X;18)(p11.2;q11.2) is present in nearly all synovial sarcomas, providing strong evidence for the diagnosis of this tumor.
Last updated: 7/11/2011
- Synovial Sarcoma: Questions and Answers. National Cancer Institute (NCI). 2005; http://www.cancer.gov/cancertopics/factsheet/Sites-Types/synovial. Accessed 7/11/2011.
- Ruggiero A. Synovialsarcoma. Orphanet. March 2004; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=3273. Accessed 7/11/2011.