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Genetic and Rare Diseases Information Center (GARD)

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Cutaneous mastocytosis

Other Names for this Disease
  • Diffuse cutaneous mastocytosis
  • Mastocytoma
  • Telangiectasia macularis eruptiva perstans
  • Urticaria pigmentosa
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How might cutaneous mastocytosis be treated?

Therapy for cutaneous mastocytosis aims to relieve symptoms.  Medications such as antihistamines and disodium cromoglycate (cromolyn) are available to target most skin and stomach-related symptoms. [1]

Other medications may be recommended for symptoms of more severe and unusual forms of cutaneous mastocytosis.  Corticosteroid therapy, both applied to the skin (topical) and by injection, as well as aspirin may be helpful for some individuals whose symptoms don't improve with antihistamines. Some severe cases of cutaneous mastocytosis may respond to ultraviolet light therapy such as psoralen plus UV-A (PUVA). These therapies must be carefully administered by a healthcare professional due to potentially severe reactions.  [1]

Therapies that stabilize the body's immune system (immune modulators) are currently being developed. [1]
Last updated: 10/8/2012

  1. Hogan D, Mastrodomenico CM. Mastocytosis: Treatment & Medication. Medscape Reference. June 2012; Accessed 10/8/2012.

Clinical Trials & Research for this Disease

  • lists trials that are studying or have studied Cutaneous mastocytosis. Click on the link to go to to read descriptions of these studies.
  • Orphanet lists clinical trials, research studies, and patient registries enrolling people with this condition. Click on Orphanet to view the list.