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Genetic and Rare Diseases Information Center (GARD)

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Hypersensitivity vasculitis

Other Names for this Disease
  • Leukocytoclastic angiitis
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Hypersensitivity vasculitis is an extreme reaction to a drug, infection, or foreign substance that leads to inflammation and damage to blood vessels of the skin. Signs and symptoms may include purple-colored spots and patches on the skin; skin lesions on the legs, buttocks, or trunk; blisters on the skin; hives (urticaria); and/or open sores with dead tissue (necrotic ulcers). This condition is caused by an allergic reaction to a drug or other foreign substance. This condition usually goes away over time; but on occasion, people can have repeated episodes.[1]
Last updated: 12/14/2011


  1. Allergic vasculitis. MedlinePlus. 2011; Accessed 12/14/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

Please contact us with your questions about Hypersensitivity vasculitis. We will answer your question and update these pages with new resources and information.

Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.

In Depth Information

  • Medscape References has articles on hypersensitivity vasculitis and leukocytoclastic vasculitis. You may need to register to view the information online, but registration is free.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.