Neurofibromatosis type 1
Other Names for this Disease
- Recklinghausen's disease
- Type 1 neurofibromatosis
- Von Recklinghausen disease
Your QuestionI have neurofibromatosis type 1, and in the last couple of years I have developed severe skin itching. Do you think the itching has anything to do with NF1?
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Skin itching, or pruritus, can be a symptom of neurofibromatosis type 1. Neurofibromas under the skin can be very itchy, especially when they are growing. This intense itchiness may interfere with sleep and other daily activities. A type of antihistamine medication called ketotifen has been effective in treating this symptom.
- Riccardi VM. Genetic Predisposition to and Histogenesis of Neurofibromas and Neurofibrosarcoma in NeurofibromatosisType 1. Neurosurgical Focus. August 29, 2007; http://www.medscape.com/viewarticle/561646_3. Accessed 6/29/2009.
- Riccardi VM. Archives of Dermatology. May 1993; 129:587-581. http://www.ncbi.nlm.nih.gov/pubmed/8481017. Accessed 6/29/2009.