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Other Names for this Disease
- Intestinal lipodystrophy
- Intestinal lipophagic granulomatosis
- Secondary Non-tropical Sprue
- Tropheryma whippelii infection
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 The disorder usually occurs in the gastrointestinal system, but may affect any part of the body including the heart, lungs, brain, joints, and eyes. In the gastrointestinal system it interferes with the body's ability to absorb certain nutrients. This leads to a condition known as malabsorption. Whipple disease causes weight loss, incomplete breakdown of carbohydrates or fats, and malfunctions of the immune system. It is caused by infection from bacteria called Tropheryma whippelii. When recognized and treated, Whipple disease can usually be cured. Untreated, the disease may be fatal.Whipple disease is a multi-system infectious bacterial disease that interferes with the body's ability to metabolize fats.
Last updated: 8/1/2012
- NINDS Whipple's Disease Information Page. National Institute of Neurological Disorders and Stroke (NINDS). March 22, 2011; http://www.ninds.nih.gov/disorders/whipples/whipples.htm. Accessed 8/1/2012.
- Whipple's Disease. National Digestive Diseases Information Clearinghouse (NDDIC). April 30, 2012; http://digestive.niddk.nih.gov/ddiseases/pubs/whipple/index.htm. Accessed 8/1/2012.
- Dugdale DC, Longstreth GF. Whipple's disease. MedlinePlus. May 1, 2012; http://www.nlm.nih.gov/medlineplus/ency/article/000209.htm. Accessed 8/1/2012.
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