Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Whipple disease

Other Names for this Disease
  • Intestinal lipodystrophy
  • Intestinal lipophagic granulomatosis
  • Secondary Non-tropical Sprue
  • Tropheryma whippelii infection
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Newline Maker

What symptoms have been associated with Whipple disease?

The gastrointestinal symptoms of Whipple disease include diarrhea, intestinal bleeding, abdominal pain, loss of appetite, weight loss, fatigue, and weakness.[1][2] Arthritis and fever often occur several years before intestinal symptoms develop.[2] Patients may also experience neurological symptoms, including abnormalities of eye and facial muscle movements, confusion, seizures, ataxia, memory loss, and vision impairment.[1]

Last updated: 8/1/2012

  1. NINDS Whipple's Disease Information Page. National Institute of Neurological Disorders and Stroke (NINDS). March 22, 2011; Accessed 8/1/2012.
  2. Whipple's Disease. National Digestive Diseases Information Clearinghouse (NDDIC). April 30, 2012; Accessed 8/1/2012.