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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Megalocytic interstitial nephritis


Other Names for this Disease
  • Interstitial megalocytic nephritis
  • Transplant megalocytic interstitial nephritis (type)
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Overview


Megalocytic interstitial nephritis is a rare chronic kidney disease that is characterized by inflammation of the kidney. It is similar to malakoplakia of the kidney. In this condition the inflammation is caused by various infiltrate, particularly histiocytes. A histiocyte is a type of immune cell that eats foreign substances in an effort to protect the body from infection.
Last updated: 4/2/2009

References

  1. Tolkoff-Rubin NE, Rubin RH, Contran RS. Urinary Tract Infection, Pyelonephritis, and Reflux Nephropathy. In: Brenner BM, Levine SA. Brenner & Rector's THE KIDNEY 8th ed. Philadelphia, PA: 2008;
  2. Kapasi H, Roberstson S, Futter N. Diagnosis of renal malacoplakia by fine needle aspiration cytology. A case report. Acta Cytol. 1998 Nov-Dec;
  3. Krupp G et al. Tumefactive megalocytic interstitial nephritis in a patient with Escherichia coli bacteremia. Am J Kidney Dis. 1995 Jun;
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