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Genetic and Rare Diseases Information Center (GARD)

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Punctate porokeratosis


Other Names for this Disease

  • Porokeratosis punctata palmaris et plantaris
  • PPPP
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Overview

Punctate porokeratosis is a skin condition that appears in adulthood as many, tiny, ridgelike bumps on the palms of the hands and soles of the feet.  These bumps may slowly spread over the skin and usually do not cause symptoms, though they sometimes cause itching or discomfort while walking.  Individuals with this condition often develop other types of porokeratosis as well.  The cause of punctate porokeratosis is unknown, though genetic factors, a weakened immune system (immunodeficiency), or previous injury to the skin (for example, a burn) have been suggested as possible risk factors.   Treatment depends on the size, location, and aggressiveness of porokeratosis in each affected individual; it may include observation only, medication, or surgery.[1]
Last updated: 8/24/2012

References

  1. Spencer LV . Porokeratosis. Medscape Reference. May 30, 2012; http://emedicine.medscape.com/article/1059123-overview#a0101. Accessed 8/21/2012.
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  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Punctate porokeratosis. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Porokeratosis punctata palmaris et plantaris
  • PPPP
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.