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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Punctate porokeratosis


Other Names for this Disease

  • Porokeratosis punctata palmaris et plantaris
  • PPPP
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Treatment

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How might punctate porokeratosis be treated?

Treatment depends on the size, location, and aggressiveness of punctate porokeratosis.  Affected individuals are recommended to visit their personal physician regularly to watch for signs of skin cancer, limit sun exposure to the affected area, and use moisturizers as needed.[1]  5-fluorouracil cream has been found to be an effective treatment.  A group of medications called retinoids (including acitretin and isotretinoin), as a pill or cream, may be another treatment option.[1]  If a skin cancer develops from porokeratosis, surgery is recommended.[2]
Last updated: 8/24/2012

References
  1. Sertznig P, von Felbert V, Megahed M. Porokeratosis: present concepts. Journal of the Academy of Dermatology and Venereology. 2012; 26:404-412. http://www.ncbi.nlm.nih.gov/pubmed/21929548. Accessed 8/16/2012.
  2. Spencer LV . Porokeratosis. Medscape Reference. May 30, 2012; http://emedicine.medscape.com/article/1059123-overview#a0101. Accessed 8/21/2012.


Clinical Trials & Research for this Disease

  • The Centers for Mendelian Genomics program is working to discover the causes of rare genetic disorders. For more information about applying to the research study, please visit their website.
Other Names for this Disease
  • Porokeratosis punctata palmaris et plantaris
  • PPPP
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.