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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Pineocytoma


Other Names for this Disease

  • Pinealocytoma
  • Pinealoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

What is a pineocytoma?

How might a pineocytoma be treated?

What is a pineocytoma?

A pineocytoma is a tumor of the pineal gland, a small organ in the brain that makes melatonin (a sleep-regulating hormone). Pineocytomas most often occur in adults as a solid mass, although they may appear to have fluid-filled (cystic) spaces on images of the brain. Signs and symptoms of pineocytomas include headaches, nausea, hydrocephalus, vision abnormalities, and Parinaud syndrome.[1] Pineocytomas are usually slow-growing and rarely spread to other parts of the body.[2] Treatment includes surgery to remove the pineocytoma; most of these tumors do not regrow (recur) after surgery.[3]
Last updated: 11/13/2014

How might a pineocytoma be treated?

Because pineocytomas are quite rare, there are no consensus guidelines on the best treatment for these tumors.[4] However, surgery to remove the entire tumor is considered the standard treatment. Because these tumors are located deep in the brain, it is important that the risks of surgery be carefully considered in each person.[3]  Radiation therapy is sometimes used following surgery to destroy any tumor cells that may remain, but the benefit of this additional treatment is questionable.[4]
Last updated: 11/13/2014

References
  1. Maria Moschovi, MD; George P Chrousos, MD. Pineal Gland Masses. UpToDate. October 2013;
  2. Gaillard F, Jones J. Masses of the pineal region: clinical presentation and radiographic features. Postgraduate Medical Journal. 2010; 86:597-607. http://www.ncbi.nlm.nih.gov/pubmed/20971711. Accessed 12/13/2011.
  3. Dahiya S, Perry A. Pineal Tumors. Advances in Anatomic Pathology. 2010; 17:419-427. http://www.ncbi.nlm.nih.gov/pubmed/20966647. Accessed 12/13/2011.
  4. Clark AJ, Ivan ME, Sughrue ME, Yang I, Aranda D, Han SJ, Kane AJ, Parsa AT. Tumor control after surgery and radiotherapy for pineocytoma. Journal of Neurosurgery. 2010; 113:319-324. http://www.ncbi.nlm.nih.gov/pubmed/20136388. Accessed 12/13/2011.


Other Names for this Disease
  • Pinealocytoma
  • Pinealoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.