Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.


Genetic and Rare Diseases Information Center (GARD)

Print friendly version

HTLV-1 associated myelopathy/tropical spastic paraparesis

Other Names for this Disease
  • Human T-cell leukemia virus type 1 associated myelopathy/tropical spastic paraparesis
  • Tropical spastic paraparesis (formerly)
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


Newline Maker

What are the signs and symptoms of HTLV-1 associated myelopathy/tropical spastic paraparesis?

Signs and symptoms of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) vary but may include:[1][2]

  • Progressive weakness 
  • Stiff muscles 
  • Muscle spasms 
  • Backache
  • A 'weak' bladder 
  • Constipation

Rarely HAM/TSP may cause:[2]

  • Uveitis 
  • Arthritis
  • Inflammation of the lung 
  • Polymyositis 
  • Dry eyes (keratoconjunctivitis sicca) 
  • Skin inflammation (infectious dermatitis)
Last updated: 3/16/2011

  1. Tropical Spastic Paraparesis/HTLV-1–Associated Myelopathy. The Merck Manuals: Online Medical Library. August 2007; Accessed 3/17/2008.
  2. Tropical Spastic Paraparesis. National Institute of Neurological Disorders and Stroke. May 9, 2007; Accessed 3/17/2008.