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Genetic and Rare Diseases Information Center (GARD)

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Diabetic mastopathy

Other Names for this Disease
  • Diabetic fibrous breast disease
  • Diabetic fibrous mastopathy
  • Lymphocytic mastitis
  • Lymphocytic mastopathy
  • Sclerosing lymphocytic lobulitis
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Your Question

I was diagnosed with diabetic mastopathy a few years ago and had a lumpectomy. Some of it was left behind, so not to cause disfigurement. Since that time I experience breast pain and throbbing a couple times a week. Is this pain connected to my breast disorder? Do you think it has spread, or simply reoccurred in other areas of the breast? Is pain normal? I worry about it becoming malignant also.

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

What is diabetic mastopathy?

Diabetic mastopathy are noncancerous lesions in the breast most commonly diagnosed in premenopausal women with type 1 diabetes.[1][2][3] The cause of this condition is unknown.[1][2][3][4][5] Symptoms may include hard, irregular, easily movable, discrete, painless breast mass(es).[1][4][6]
Last updated: 7/24/2013

What are the symptoms of diabetic mastopathy?

Common symptoms of diabetic mastopathy include hard, irregular, easily movable, discrete, painless breast mass(es).[1] This condition can involve one or both breasts and can affect males and females.[1] The breast lesions may not be palpable in some patients.[1] Patients with diabetic mastopathy who have had insulin-requiring diabetes for a long time (>15 years) commonly have other diabetes complications as well (e.g., thyroid, eye, and joint involvement).[1][5]
Last updated: 10/15/2009

What causes diabetic mastopathy?

The cause of diabetic mastopathy is unknown. Theories include an autoimmune reaction, genetic factors such as human leukocyte antigen (HLA) type, association with insulin therapy, and association with hyperglycemia.[1][2][5]
Last updated: 7/24/2013

Can diabetic mastopathy recur?

Yes. Diabetic mastopathy can recur. In patients with recurrence, the recurrence tends to be in the same location involving more breast tissue than previously seen.[1][3]
Last updated: 7/24/2013

Does diabetic mastopathy increase a person's risk for developing breast cancer?

No. Diabetic mastopathy does not increase a person's risk for developing breast cancer.[1][2][4] The small number of reported cases (three) which describe malignancy in patients with diabetic mastopathy are believed to be due to coincidence. There is no pathologic literature linking diabetic mastopathy with malignancy.[5]
Last updated: 10/15/2009

What are the symptoms of breast cancer?

Common symptoms of breast cancer include, a change in how the breast or nipple feels, a lump or thickening in or near the breast or in the underarm area, nipple tenderness, a change in how the breast or nipple looks, a change in the size or shape of the breast, a nipple turned inward into the breast, scaly, red, or swollen skin of the breast, areola, or nipple. Other symptoms include ridges or pitting of the breast so that it looks like the skin of an orange and nipple discharge (fluid).[6]
Last updated: 7/24/2013

Is pain in the breast a symptom of breast cancer?

Early breast cancer usually does not cause pain. Still, a person should see his/her health care provider about breast pain or any other symptom that does not go away. Most often, these symptoms are not due to cancer. Other health problems may also cause them. Any person with these symptoms should tell their doctor so that problems can be diagnosed and treated as early as possible.[6]
Last updated: 7/24/2013

Who should I talk to if I am concerned I may have breast cancer?

If you are concerned that you may have breast cancer we recommend that you speak with your health care provider.
Last updated: 7/24/2013