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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Primary orthostatic tremor


Other Names for this Disease
  • Orthostatic tremor, primary
  • OT
  • Shaky leg syndrome
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Overview


Primary orthostatic tremor is a movement disorder characterized by rhythmic muscle contractions that occur in the legs and trunk immediately after standing. It may be perceived more as an unsteadiness than an actual tremor. The tremor may disappear or improve when a person is sitting or walking.[1][2] Over time, the tremors may become more severe, affecting quality of life and causing increasing disability.[2][3] In some cases, primary orthostatic tremor may occur with other movement disorders.[3] Individuals with primary orthostatic tremor may be treated with clonazepam and primidone.[1] The cause of this condition is unknown.[2]
Last updated: 3/17/2014

References

  1. Tremor Fact Sheet. National Institute of Neurological Disorders and Stroke (NINDS). February 10, 2014; http://www.ninds.nih.gov/disorders/tremor/detail_tremor.htm. Accessed 3/17/2014.
  2. Jankovic J. Primary Orthostatic Tremor. National Organization for Rare Disorders (NORD). 2014; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1133/viewAbstract. Accessed 3/17/2014.
  3. Mestre TA, Lang AE, Ferreira JJ, Almeida V, de Carvalho M, Miyasaki J, Chen R, Fox S. Associated movement disorders in orthostatic tremor. J Neurol Neurosurg Psychiatry. 2012; 83:725-729. http://jnnp.bmj.com/content/83/7/725.abstract. Accessed 3/17/2014.
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