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Hashimoto's encephalitis

Other Names for this Disease
  • Hashimoto's encephalopathy
  • Steroid-responsive encephalopathy associated with autoimmune thyroiditis
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Hashimoto's encephalitis (HE) is a rare autoimmune disease with neurological and psychiatric features.[1][2][3][4] The condition is characterized by high titers of antithyroid antibodies in blood and cerebrospinal fluid (CSF).[1][2][4] Two types of HE have been suggested: a vasculitic type characterized by multiple relapsing-remitting stroke-like episodes and mild cognitive impairment, and a diffuse progressive type characterized by dementia and psychiatric symptoms.[1][3] Patients are mostly women.[1] Treatment includes steroids, plasmapheresis (plasma exchange), or immunosuppressant medications.[1][2][4]
Last updated: 4/16/2010


  1. Mijajlovic M, Mirkovic M, Dackovic, J et al.. J Neurol Sci. 2010; Accessed 4/16/2010.
  2. Mocellin R, Walterfang M, Velakoulis D. CNS Drugs. 2007; Accessed 4/16/2010.
  3. Marshall GA, Doyle JJ. J Neuropsychiatry Clin Neurosci. 2006; Accessed 4/16/2010.
  4. Schiess N, Pardo CA. Ann N Y Acad Sci. 2008; Accessed 4/16/2010.
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In Depth Information

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