Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Acanthosis nigricans


Other Names for this Disease

  • AN
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

How can acanthosis nigricans (AN) be treated?

There is no specific treatment for AN. Treatments are used mostly to improve cosmetic appearance and include topical retinoids,  vitamin D creams (such as calcipotriol), dermabrasion and laser therapy. Oral retinoid pills have also been used to treat AN, but are not used for most patients because of the multiple side effects and development problems associated with the treatment. Treatment may also focus on trying to correct the underlying disease that causes AN to develop. Often correcting the underlying disease improves the skin symptoms. Some steps that can be taken depending on the underlying disease include: correcting hyperinsulinaemia through diet and medication, losing weight with obesity-associated AN, removing or treating a tumor, or stopping medications that cause AN.[1][2]
Last updated: 8/18/2014

References
  1. Braunstein I. Acanthosis nigricans. In: Callen J, Ofori AO. UpToDate. Waltham, MA: UpToDate; March, 2014; http://www.uptodate.com/contents/acanthosis-nigricans. Accessed 8/15/2014.
  2. Acanthosis nigricans. DermNet NZ. New Zealand: DermNet New Zealand Trust; December 9, 2009; http://www.dermnetnz.org/systemic/acanthosis-nigricans.html. Accessed 8/15/2014.


Clinical Trials & Research for this Disease

  • The Centers for Mendelian Genomics program is working to discover the causes of rare genetic disorders. For more information about applying to the research study, please visit their website.
  • ClinicalTrials.gov lists trials that are studying or have studied Acanthosis nigricans. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • AN
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.