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Hyperparathyroidism, primary

Other Names for this Disease
  • Primary hyperthyroidism
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Hyperparathyroidism is an endocrine disorder in which the parathyroid glands in the neck produce too much parathyroid hormone (PTH).[1] Signs and symptoms are often mild and nonspecific, such as a feeling of weakness and fatigue, depression, or aches and pains. With more severe disease, a person may have a loss of appetite, nausea, vomiting, constipation, confusion or impaired thinking and memory, and increased thirst and urination. Patients may have thinning of the bones without symptoms, but with risk of fractures.[2] There are two main types of hyperparathyroidism: primary hyperparathyroidism and secondary hyperparathyroidism.[1] Surgery to remove the parathyroid gland(s) is the main treatment for the disorder. Some patients with mild disease do not require treatment.[2]
Last updated: 4/2/2012


  1. Eckman AS. Hyperparathyroidism. MedlinePlus. August 31, 2010; Accessed 4/2/2012.
  2. Hyperparathyroidism. National Endocrine and Metabolic Diseases Information Service (NEMDIS]. May 2006; Accessed 4/2/2012.
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Basic Information

  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Endocrine and Metabolic Diseases Information Service, a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), provides information on this topic. Click on the link to view the information on this topic.

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  • Medscape Reference has four articles on this topic from the perspective of Endocrinology, Pediatrics, Radiology and Emergency Medicine. You may need to register to view the information online, but registration is free. Click on the links above to view the articles from this medical reference Web site.
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