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Genetic and Rare Diseases Information Center (GARD)

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Paget disease of bone

*

* Not a rare disease

Other Names for this Disease

  • Osteitis deformans
  • PDB
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Paget disease of bone is a disorder that involves abnormal bone destruction and regrowth, which results in deformity. This condition can affect any of the bones in the body; but most people have it in their spine, pelvis, skull, or leg bones. The disease may affect only one bone or several bones; but it does not affect the entire skeleton. Bones with Paget disease may break more easily, and the disease can lead to other health problems. The cause of Paget disease is unknown, although it may be associated with faulty genes or viral infections early in life.[1][2]
Last updated: 12/12/2011

References

  1. Paget’s disease of the bone. MedlinePlus. November 2009; http://www.nlm.nih.gov/medlineplus/ency/article/000414.htm. Accessed 12/12/2011.
  2. What Is Paget's Disease of Bone?. NIH Osteoporosis and Related Bone Diseases ~ National Resource Center. May 2009; http://www.niams.nih.gov/Health_Info/Bone/Pagets/pagets_disease_ff.asp. Accessed 12/12/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

Please contact us with your questions about Paget disease of bone. We will answer your question and update these pages with new resources and information.

Basic Information

  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases, the training of basic and clinical scientists to carry out this research, and the dissemination of information on research progress in these diseases. Click on the link to view information on this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Paget disease of bone. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Osteitis deformans
  • PDB
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.