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Genetic and Rare Diseases Information Center (GARD)

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Autoimmune progesterone dermatitis


Other Names for this Disease
  • APD
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Autoimmune progesterone dermatitis (APD) is primarily characterized by a recurrent skin rash that varies in severity depending on the phase of the menstrual cycle. The rash generally appears during the second half of the cycle when levels of the hormone, progesterone, begin to rise and it subsides shortly after menstruation. Although the exact underlying cause of APD is not well understood, it is thought to involve an abnormal immune reaction (autoimmune response) triggered by a woman's own progesterone. Depending on the severity of the condition, treatment may include topical (applied to the skin) medications, systemic corticosteroids, hormone therapy to suppress the production of progesterone, and/or surgical removal of the ovaries.[1][2][3]
Last updated: 4/16/2015

References

  1. Tami Maguire. Autoimmune Progesterone Dermatitis. Dermatology Nursing. 2009; 21(4):190-192. http://www.medscape.com/viewarticle/712365. Accessed 1/9/2012.
  2. George R, Badawy SZ. Autoimmune progesterone dermatitis: a case report. Case Rep Obstet Gynecol. 2012; Epub 2012 Aug 9:
  3. Autoimmune progesterone dermatitis. DermNet NZ. December 2013; http://dermnetnz.org/reactions/progesterone-dermatitis.html.
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Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.

In Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Autoimmune progesterone dermatitis. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • APD
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.