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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Membranous nephropathy


Other Names for this Disease

  • Extramembranous glomerulonephritis
  • Glomerulonephritis, membranous
  • Idiopathic membranous nephropathy
  • Membranous glomerulonephritis
  • Membranous GN
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Overview

Membranous nephropathy is a kidney disease characterized by inflammation of the structures inside the kidney that help filter wastes and fluids.[1] When the glomerular basement membrane becomes thickened, it does not work normally, allowing large amounts of protein to be lost in the urine. Symptoms develop gradually and may include swelling, fatigue, weight gain, and high blood pressure. In many cases, the underlying cause of membranous nephropathy is not known. Some cases are associated with other conditions (lupus), infections (hepatitis B and C), cancer or as a side effect of certain medications.[1][2] The goal of treatment is to reduce symptoms and slow the progression of the disease.[1] 
Last updated: 9/2/2014

References

  1. Silberberg C. Membranous nephropathy. MedlinePlus. September 8, 2013; http://www.nlm.nih.gov/medlineplus/ency/article/000472.htm. Accessed 9/2/2014.
  2. Membranous Nephropathy (MN). Nephrotic Syndrome Study Network (NEPTUNE). http://www.rarediseasesnetwork.org/NEPTUNE/patients/learnmore/MN/. Accessed 9/2/2014.
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Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Merck Manual for health care professionals provides information on Membranous nephropathy.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
Other Names for this Disease
  • Extramembranous glomerulonephritis
  • Glomerulonephritis, membranous
  • Idiopathic membranous nephropathy
  • Membranous glomerulonephritis
  • Membranous GN
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.