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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Charcot-Marie-Tooth disease type 2F


Other Names for this Disease
  • Charcot Marie Tooth disease type 2F
  • Charcot-Marie-Tooth disease, axonal, Type 2F
  • Charcot-Marie-Tooth disease, neuronal, Type 2F
  • Charcot-Marie-Tooth neuropathy, type 2F
  • CMT 2F
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Inheritance


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How is Charcot-Marie-Tooth disease type 2F inherited?

Charcot-Marie-Tooth disease type 2F is inherited in an autosomal dominant manner. This means that only one mutated copy of the gene in each cell is sufficient to cause the condition. Most affected individuals inherit the mutated gene from an affected parent, but in some cases the mutation occurs for the first time in the affected individual (de novo mutation).[1] When an individual with an autosomal dominant condition has children, each child has a 50% (1 in 2) chance to inherit the mutated gene and have the condition.
Last updated: 8/1/2012

References
  1. Thomas D. Bird. Charcot-Marie-Tooth Neuropathy Type 2. GeneReviews. July 5, 2012; http://www.ncbi.nlm.nih.gov/books/NBK1285/. Accessed 7/31/2012.