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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Chiari malformation type 1

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* Not a rare disease
Other Names for this Disease
  • Arnold Chiari malformation type I
  • Chiari malformation type I
  • Chiari type I malformation
More Names
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Overview


Chiari malformation type 1 is a structural abnormality of the cerebellum, the part of the brain that controls balance. It involves the extension of the lower part of the cerebellum into the foramen magnum (the large hole at the base of the skull which allows passage of the spinal cord), without involving the brainstem. Normally, only the spinal cord passes through this opening. This malformation is the most common type of Chiari malformation and may not cause any symptoms.[1] Depending on the symptoms present and severity, some individuals may not require treatment while others may require pain medications or surgery.[2][3]


References

  1. Chiari Malformation Fact Sheet. National Institute of Neurological Disorders and Stroke Web site. http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm. Accessed December 22, 2009.
  2. Chiari Malformation Fact Sheet. NINDS. http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm#194173087. Accessed March 11, 2012.
  3. Peyman Pakzaban. Chiari Malformation. eMedicine. http://emedicine.medscape.com/article/1483583-overview. Accessed March 11, 2012.
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General Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Chiari malformation type 1. Click on the link to view a sample search on this topic.
  • The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Chiari malformation type 1. Click on the link to go to OMIM and review these resources.