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Sinonasal undifferentiated carcinoma

Other Names for this Disease
  • Highly aggressive undifferentiated carcinoma of the nasal cavity and paranasal sinuses
  • SNUC
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Sinonasal undifferentiated carcinoma (SNUC) is a type of cancer that develops in the sinuses of the head.  SNUC occurs when cells from the layer of tissue that lines the sinuses (called the epithelium) rapidly increase in number, forming a mass.  The first symptoms of SNUC may include difficulty breathing though the nose or mild facial pain.  As SNUC progresses, other symptoms may include nosebleeds, facial numbness, or tingling in the face.  SNUC is an aggressive cancer, meaning it grows rapidly and has a tendency to spread into healthy tissues nearby and to more distant parts of the body (metastasis).  Treatment may include surgery, chemotherapy, and radiation therapy.[1]
Last updated: 1/22/2013


  1. Schmidt ER, Berry RL. Diagnosis and treatment of sinonasal undifferentiated carcinoma: report of a case and review of the literature. Journal of oral and maxillofacial surgery. 2008; 66:1505-1510. Accessed 1/15/2013.
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