Hepatocellular carcinoma, childhood
Other Names for this Disease
- pediatric HCC
- Pediatric hepatocellular carcinoma
Your QuestionWhat causes hepatocellular carcinoma in children? Was it environmental or genetic factors?
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In addition, various other reported risk factors for developing hepatocellular carcinoma include: male sex, co-infection with other viral liver disease, co-infection with HIV, alcohol abuse, family history of this carcinoma, increased hepatic iron, increased serum alanine aminotransferase levels, exposure to aflatoxin B1 by food contamination, genetic variants of glutathione S-transferase, and various metabolic liver disorders.
Chronic Epstein Barr virus infections have also been suggested to play a role in the development of hepatocellular carcinoma in Asian patients. This association remains to be confirmed in other populations.
- Rosenthal P. Journal of Pediatric Gastroenterology and Nutrition. 2008; http://www.ncbi.nlm.nih.gov/pubmed/18367947. Accessed 2/11/2009.
- Lack E, Neave C, Vawter G. Cancer. February 18, 2009; http://www.ncbi.nlm.nih.gov/pubmed/6311396. Accessed 1/1/1983.
- Czauderna P. Med Pediatr Oncol. 2002; http://www.ncbi.nlm.nih.gov/pubmed/12228910. Accessed 2/18/2009.
- Crum N. Southern Medical Journal. 2006; http://www.ncbi.nlm.nih.gov/pubmed/16711324. Accessed 2/11/2009.
- Axelrod DA, van Leeuwen DJ. Hepatocellular carcinoma. eMedicine. 2008; http://emedicine.medscape.com/article/197319-overview. Accessed 2/11/2009.