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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Pseudoangiomatous stromal hyperplasia

*


* Not a rare disease
Other Names for this Disease
  • Mammary pseudoangiomatous stromal hyperplasia
  • PASH
  • Pseudoangiomatous stromal hyperplasia of the breast
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Overview



What is pseudoangiomatous stromal hyperplasia (PASH)?

Is treatment available for pseudoangiomatous stromal hyperplasia (PASH)?


What is pseudoangiomatous stromal hyperplasia (PASH)?

Pseudoangiomatous stromal hyperplasia (PASH) is a type of non-cancerous breast lesion. It typically affects women in the reproductive age group.[1] The size of the lesion varies, but small microscopic PASH is much more common than larger masses. Microscopic PASH is often an incidental finding in breast biopsies done for other non-cancerous or cancerous lesions. Tumorous PASH presents as a firm, painless breast mass or a dense region on a mammogram.[2][1] 
Last updated: 4/8/2011

Is treatment available for pseudoangiomatous stromal hyperplasia (PASH)?

Surgical removal of the PASH lesions has been performed in some individuals. A wide margin around the mass may be removed to prevent recurrence. Although PASH lesions often grow over time and may recur, they are neither associated with malignancy (cancer) nor considered to be premalignant (pre-cancerous).[2] According to the medical text, CONN's Current Therapy 2007, approximately 7 percent of people experience a recurrence of PASH.[3]
Last updated: 7/19/2013

References
  1. Virk RK, Khan A. Pseudoangiomatous stromal hyperplasia: an overview. Arch Pathol Lab Med. 2010 Jul;
  2. Cyrlak D, Carpenter PM. Breast imaging case of the day: Pseudoangiomatous stromal hyperplasia. Radiographics. 1999; 19:1086-1088. http://radiographics.rsnajnls.org/cgi/content/full/19/4/1086. Accessed 3/4/2008.
  3. Sukumvanich P, Borgen P. Diseases of the Breast. In: Rakel RE, Bope ET. CONN'S Current Therapy 2007, 59th ed. Philadelphia, PA: Saunders Elsevier; 2007..