Other Names for this Disease
- Calcifying epithelioma of Malherbe
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The cause of all pilomatrixomas is not fully known, but investigators have shown that at least 75% of individuals with pilomatrixomas have mutations in the CTNNB1 gene. This gene is responsible for a protein that is needed to regulate cell growth and attachment. When the gene is not working properly, it can result in abnormal cell growth. It is thought that the tumors typically arise from cells that interact with hair follicle cells.
Last updated: 10/30/2014
- Jaggi Rao, Andrew Lin. Pilomatrixoma. Medscape Reference. March 3, 2014; http://emedicine.medscape.com/article/1058965-overview#a0104. Accessed 10/30/2014.
- Pilomatricoma. Genetics Home Reference. June 2012; http://ghr.nlm.nih.gov/condition/pilomatricoma. Accessed 10/30/2014.