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Genetic and Rare Diseases Information Center (GARD)

Other Names for this Disease
  • GSM 1
  • Hereditary chin tremor/myoclonus
  • Hereditary geniospasm
  • Trembling chin
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Hereditary geniospasm is a movement disorder that causes episodes of involuntary tremors of the chin and lower lip. The episodes may last anywhere from a few seconds to hours and may occur spontaneously or be brought on by stress. The episodes usually first appear in infancy or childhood and tend to lessen in frequency with age. Hereditary geniospasm is believed to be inherited in an autosomal dominant pattern. Although the exact gene(s) that cause the condition are unknown, it has been suggested that mutations in a gene on chromosome 9 may be responsible in some families.[1][2]
Last updated: 6/5/2013


  1. Geniospasm 1. OMIM (Online Mendelian Inheritance in Man). June 30, 2004; Accessed 7/21/2009.
  2. Jarman PR, Wood NW, Davis MT, Davis PV, Bhatia KP, Marsden CD, Davis MB. Am. J. Hum. Genet. 1997; Accessed 7/21/2009.
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In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Geniospasm. Click on the link to view a sample search on this topic.

Selected Full-Text Journal Articles