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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Cerulean cataract


Other Names for this Disease

  • Cataract, congenital, blue dot type 1
  • Cataract, congenital, cerulean type 1
  • CCA1
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

What are cerulean cataracts?

How might cerulean cataracts be treated?

What are cerulean cataracts?

Cerulean cataracts are opaque areas that develop in the lens of the eye that often have a bluish or whitish color. They may be present at birth or develop in very early childhood, but may not be diagnosed until adulthood.[1] They are usually bilateral and progressive.[2] Infants can be asymptomatic, but may also be visually impaired from birth and develop nystagmus and amblyopia.[2] In adulthood, the cataracts may progress, making lens removal necessary.[1] Cerulean cataracts may be caused by mutations in several genes, including the CRYBB2, CRYGD, and MAF genes, and are inherited in an autosomal dominant manner. No treatment is known to prevent cerulean cataracts, but frequent evaluations and cataract surgery are typically required to prevent amblyopia as the opacities progress.[2]
Last updated: 4/6/2011

How might cerulean cataracts be treated?

No treatment is known to prevent cerulean cataracts, and there is currently no cure for the condition. Frequent eye evaluations and eventual cataract surgery are typically required to prevent amblyopia (vision loss) as the opacities progress.[2] The symptoms of early cataracts may be improved with new eyeglasses, brighter lighting, anti-glare sunglasses, or magnifying lenses. However, if these measures do not help, surgery is often the only effective treatment. Surgery involves removing the cloudy lens and replacing it with an artificial lens. Surgery is often considered when vision loss regularly interferes with everyday activities, such as driving, reading, or watching TV.[3]
Last updated: 4/6/2011

References
  1. Marla J. F. O'Neill et al. CATARACT, CONGENITAL, CERULEAN TYPE, 1; CCA1. OMIM. June 21, 2006; http://www.ncbi.nlm.nih.gov/omim/115660. Accessed 4/6/2011.
  2. Cataracts, Congenital Cerulean. University of Arizone. 2010; http://disorders.eyes.arizona.edu/disorders/cataracts-congenital-cerulean. Accessed 4/6/2011.
  3. Facts About Cataract. National Eye Institute. April 2011; http://www.nei.nih.gov/health/cataract/cataract_facts.asp. Accessed 4/6/2011.


Other Names for this Disease
  • Cataract, congenital, blue dot type 1
  • Cataract, congenital, cerulean type 1
  • CCA1
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.