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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Linear porokeratosis


Other Names for this Disease
  • Congenital facial linear porokeratosis (type)
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Your Question

My daughter has linear porakeratosis and is going to have photodynamic light therapy.  She had scalded skin syndrome when she was a baby: will she still be able to recieve the treatment and will she need pain relief?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

How might linear porokeratosis be treated?

Because linear porokeratosis is a rare condition, there is no established treatment protocol.  Protection from sun exposure and regular visits to a doctor to check for skin cancer are encouraged as routine care.  Treatment options depend on the size, location, and severity of the characteristic skin markings.  Several medications (5-fluorouracil, acitretin) have been shown to be effective for treating this condition in a small number of patients.[1]  We identified a single report of photodynamic therapy being used to successfully treat an individual with linear porokeratosis.[2]  Surgery is recommended to remove any skin cancer that may develop.[1]
Last updated: 11/17/2011

If an individual had scalded skin syndrome as a baby, can she undergo photodynamic therapy for linear porokeratosis?

After a review of the medical literature, we did not identify any reports of an individual with linear porokeratosis who also had a history of scalded skin syndrome (an infection of the skin that can cause blisters and skin damage).  The one patient with linear porokeratosis treated with photodynamic therapy did not need anesthesia during this treatment because he experienced only a mild burning sensation, skin redness (erythema), and skin inflammation.[2]
Last updated: 11/17/2011

References