Alpha mannosidosis type 2
Other Names for this Disease
- Alpha-mannosidosis adult-onset form
More common signs and symptoms of alpha mannosidosis type 2 include:
Developmental delays (e.g., motor and speech)
Weakened immune system
Cerebellar disorders (e.g., ataxia)
Occasional psychiatric symptoms (e.g., depression, anxiety, or hallucinations)
Enlarged liver and spleen (with normal function)
People with alpha-mannosidosis type 2 often have distinct facial features, including large head size, large forehead, low hair line, rounded eyebrows, large ears, wide spaced teeth, overgrown gums, large tongue, protruding jaw, and flattened bridge of the nose.
- Alpha-Mannosidosis. Genetics Home Reference. 2007; http://www.ghr.nlm.nih.gov/condition/alpha-mannosidosis. Accessed 10/1/2013.
- Malm D, Nilssen O. Alpha-Mannosidosis. GeneReview. 2001; http://www.ncbi.nlm.nih.gov/books/NBK1396/. Accessed 10/1/2013.