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Epithelial basement membrane corneal dystrophy
Other Names for this Disease
- Cogan corneal dystrophy
- Corneal dystrophy, anterior basement membrane
- Map-dot-fingerprint dystrophy of cornea
- Microcystic dystrophy of the cornea
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epithelium of the cornea (the outermost region of the cornea) loses its normal clarity due to a buildup of cloudy material. It gets its name from the unusual appearance of the cornea during an eye exam. This dystrophy occurs when the epithelium's basement membrane develops abnormally, causing the epithelial cells to not properly adhere to it. This leads to recurrent epithelial erosions, which can cause blurred vision and severe pain. This condition is usually not inherited. However, families with autosomal dominant inheritance and mutations in the TGFBI gene have been identified.Epithelial basement membrane corneal dystrophy is a condition where the
Last updated: 6/30/2011
- Facts About the Cornea and Corneal Disease. National Eye Institute (NEI). June 2011; http://www.nei.nih.gov/health/cornealdisease/#j. Accessed 6/30/2011.
- Corneal dystrophy, epithelial basement membrane; EBMD. Online Mendelian Inheritance of Man (OMIM). 2009; http://www.ncbi.nlm.nih.gov/omim/121820. Accessed 6/30/2011.
- The National Eye Institute (NEI) was established by Congress in 1968 to protect and prolong the vision of the American people. Click on the link to view information on this topic.
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In Depth Information
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- The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Epithelial basement membrane corneal dystrophy. Click on the link to go to OMIM and review these resources.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Epithelial basement membrane corneal dystrophy. Click on the link to view a sample search on this topic.